Severe hospital-acquired hyponatremia in acutely ill children receiving moderately hypotonic fluids.

ABSTRACT:

Background

Hypotonic fluids have been associated with hospital-acquired hyponatremia. The incidence of life-threatening severe hyponatremia associated with hypotonic fluids has not been evaluated.

Methods

This was a population-based cohort study of 46,518 acutely ill children 15 years of age or under who visited the pediatric emergency department (ED) at Oulu University Hospital, Finland, between 2007 and 2017. We retrieved all electrolyte measurements from the comprehensive electronic laboratory system and reviewed medical records for all patients with severe hyponatremia.

Results

The overall occurrence of severe hyponatremia (serum sodium < 125 mmol/L) was found in 27 out of 46,518 acutely ill children (0.06%, 95% confidence interval 0.04-0.08%). After admission, se

SUBMITTER: Lehtiranta S 

PROVIDER: S-EPMC8816776 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature