Causal dynamics and information flow in parietal-temporal-hippocampal circuits during mental arithmetic revealed by high-temporal resolution human intracranial EEG.

ABSTRACT: Mental arithmetic involves distributed brain regions spanning parietal and temporal cortices, yet little is known about the neural dynamics of causal functional circuits that link them. Here we use high-temporal resolution (1000 Hz sampling rate) intracranial EEG from 35 participants, 362 electrodes, and 1727 electrode pairs, to investigate dynamic causal circuits linking posterior parietal cortex (PPC) with ventral temporal-occipital cortex and hippocampal regions which constitute the perceptual, visuospatial, and mnemonic building blocks of mental arithmetic. Nonlinear phase transfer entropy measures capable of capturing information flow identified dorsal PPC as a causal inflow hub during mental arithmetic, with strong causal influences from fusiform gyrus in ventral temporal-occipital c

SUBMITTER: Das A 

PROVIDER: S-EPMC8816888 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature