Associations of mental health and chronic physical illness during childhood with major depression in later life.

ABSTRACT:

Objectives

This study examined whether childhood chronic physical illness burden was associated with major depression in later life (>50 years) and whether this relationship was mediated by childhood mental health status.

Method

Data came from the 2016 United States Health and Retirement Study (n = 18,483). Logistic regression tested associations of childhood chronic physical illness burden with childhood mental health status and major depression in later life. Path analysis quantified mediation of the association between chronic physical illness burden and major depression by childhood mental health status.

Results

One standard deviation increase in childhood chronic physical illness burden was associated with 1.34 (95% CI = 1.25, 1.43) times higher odd

SUBMITTER: Bergmans RS 

PROVIDER: S-EPMC8818054 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature