Adaptive Treatment for Youth With Substance Use and Depression: Early Depression Response and Short-term Outcomes.

ABSTRACT:

Objective

To investigate prevalence and predictors of early depression response (EDR) in adolescents with substance use and depression receiving cognitive-behavioral therapy (CBT) for substance use and to test the efficacy of supplemental CBT targeting depression (CBT-D) for non-EDR adolescents in an adaptive treatment approach.

Method

At 2 sites, 95 youths (ages 14-21, mean [SD] = 17.4 [1.8]) with alcohol or cannabis use and depressive symptoms received up to 12 sessions of CBT for substance use over 14 weeks. Assessments were at baseline and weeks 4, 9, and 14. The Children's Depression Rating Scale-Revised was the primary depression measure, with a reduction of 50% or more on this scale at week 4 defining EDR. The primary substance use outcomes of alcohol use, heavy alcoh

SUBMITTER: Curry JF 

PROVIDER: S-EPMC8818057 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature