Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta-analysis.

ABSTRACT: Cancer-associated cachexia (CAC) is a wasting syndrome characterized by involuntary weight loss and anorexia. Clear definition and diagnostic criteria for CAC are lacking, which makes it difficult to estimate its prevalence, to interpret research and to compare studies. There is no standard treatment to manage CAC, but previous studies support the use of cannabinoids for cachexia in other chronic diseases including HIV and multiple sclerosis. However, only a few randomized controlled trials (RCTs) and one meta-analysis of this intervention in cancer populations are available. Non-randomized studies of interventions (NRSIs) are often excluded from reviews due to variable methodology and potential for biases. This review aimed to consider NRSIs alongside RCTs to provide a complete summary of

SUBMITTER: Simon L 

PROVIDER: S-EPMC8818598 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature