Absolute and relative grip strength as predictors of cancer: prospective cohort study of 445 552 participants in UK Biobank.

ABSTRACT:

Background

Reduced muscular strength, as measured by absolute grip strength, has been associated with increased risk of some site-specific cancers. The ability of grip strength to predict other diseases may be affected by whether it is expressed in absolute or relative terms, but the evidence for cancer is scarce. This study compared the associations of absolute and relative grip strength with all-cause and 15 site-specific cancers.

Methods

A prospective cohort study was undertaken using data from the UK Biobank. The exposure variable was grip strength, in absolute form (kilogrammes) and relative to weight, body mass index (BMI), height. and body fat mass. The outcome was incident cancer, at 15 sites and overall. Cox proportional hazard models were performed to study the ass

SUBMITTER: Parra-Soto S 

PROVIDER: S-EPMC8818619 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature