Intramuscular and intratendinous placenta-derived mesenchymal stromal-like cell treatment of a chronic quadriceps tendon rupture.

ABSTRACT:

Background

Quadriceps tendon ruptures (QTRs) are rare but debilitating injuries, often associated with chronic metabolic conditions or long-term steroid treatment. While the surgical treatment for acute QTRs is described thoroughly, no common strategy exists for the often frustrating treatment of chronic, reoccurring QTRs. The pro-angiogenic and immunomodulatory properties of placenta-derived adherent mesenchymal stromal-like (PLX-PAD) cells have been described to protect musculoskeletal tissues from inflammation and catabolic cytokine migration, yet little is known about the regenerative potential of PLX-PAD cells in repetitively damaged tendon tissue.

Case

We report the case of an 80-year-old male patient with a chronic three-time QTR of his right knee. The quadriceps tend

SUBMITTER: Maleitzke T 

PROVIDER: S-EPMC8818634 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature