Adiposity increases weight-bearing exercise-induced dyspnea despite favoring resting lung hyperinflation in COPD.

ABSTRACT:

Objectives

Our aim was to study the associations between resting lung hyperinflation, weight-bearing exercise-induced dyspnea and adipose distribution in obese and normal-weight COPD patients.

Methods

We performed a comparison between 80 obese COPD patients (COPD_OB) with 80 age- and FEV₁ matched normal-weight COPD patients (COPD_NW). Dyspnea was assessed by the mMRC scale and the Borg dyspnea score before and after a 6 min walk test. Further characterization included spirometry, body plethysmography and metronome paced tachypnea (MPT) to estimate dynamic hyperinflation. Body composition was assessed with bioelectrical impedance analysis. Associations between dyspnea scores and BMI and body composition groups were studied using logistic regress

SUBMITTER: S Z 

PROVIDER: S-EPMC8819751 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature