Health care burden and mortality of acute on chronic liver failure in Thailand: a nationwide population-based cohort study.

ABSTRACT:

Background

Accurate population-based data are required concerning the rate, economic impact, and long-term outcome from acute on chronic liver failures (ACLF) in hospitalized patients with cirrhosis. We aimed to discover time trends for the epidemiology, economic burden, and mortality of ACLF in Thailand.

Methods

We conducted a nationwide, population-based, cohort study which involved all hospitalized patients with cirrhosis in Thailand during the period between 2009 and 2013, with data from the National Health Security Office. ACLF was defined by two or more extrahepatic organ failures in patients with cirrhosis. Primary outcomes were trends in hospitalizations, hospital costs, together with inpatient mortality.

Results

The number of ACLF hospitalizations in Thailand

SUBMITTER: Chirapongsathorn S 

PROVIDER: S-EPMC8819862 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature