Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome presenting with a cervical vertebral fracture: A case report

ABSTRACT:

Background context

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare condition that can be difficult to diagnose. There are no guidelines for the treatment of SAPHO syndrome, but newer modalities of medications show promising results. We present the case of a patient who presented with a pathologic fracture of her cervical spine who ended up being diagnosed with SAPHO syndrome.

Case

A 51-year-old female presented with severe neck pain and a rash on her hands and feet. Imaging showed a C5 vertebral compression fracture and multiple sites of bony involvement concerning for malignancy or widespread infection. The patient underwent corpectomy and fusion to address the instability and cervical stenosis and was started on immunomodulating therap

SUBMITTER: Nedley A 

PROVIDER: S-EPMC8820063 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature