Congenital Chylothorax of the Newborn: A Systematic Analysis of Published Cases between 1990 and 2018.

ABSTRACT:

Background

Congenital chylothorax (CCT) of the newborn is a rare entity but the most common cause of pleural effusion in this age-group. We aimed to find the optimal treatment strategy.

Material and methods

A PubMed search was performed according to the PRISMA criteria. All cases were analyzed according to prenatal, perinatal, and postnatal treatment modalities and follow-ups.

Results

We identified 753 cases from 157 studies published between 1990 and 2018. The all-cause mortality rate was 28%. Prematurity was present in 71%, male gender dominated 57%, mean gestational age was 34 weeks, and birth weight was 2,654 g. Seventy-nine percent of newborns had bilateral CCT, the most common associated congenital anomalies with CCT were pulmonary lymphangiectasia and pulmonary

SUBMITTER: Resch B 

PROVIDER: S-EPMC8820433 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature