Can changes in skin impedance be used to monitor sedation after midazolam and during recovery from anesthesia?

ABSTRACT: It has been suggested that sympathetic activity, measured as changes in electrical skin impedance (SI), can be used to assess the adequacy of general anesthesia. Our prospective study investigated if measurements of skin impedance can determine levels of sedation induced by midazolam. Twenty-seven patients scheduled for arthroscopy requiring general anesthesia were served as their own control. These were blinded to the order of injections by telling them that they will be randomly administered a placebo (saline) orsedative agent. A DM 3900 multimeter was used for SI measurements. The degree of sedation was measured using the modified Observer's Assessment of Alertness and Sedation (mOAAS) scale. Resting SI values were noted, and all participants were then administered the placebo followed

SUBMITTER: Kurzova A 

PROVIDER: S-EPMC8820580 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature