Lifetime Risk of Heart Failure Among Participants in the Framingham Study.

ABSTRACT:

Background

The residual lifetime risk (RLR) of developing heart failure (HF) may have changed over time because of the increasing population burden of hypertension, obesity, and diabetes; greater survival after myocardial infarction; and a greater lifespan.

Objectives

The authors assessed changes in the RLR for HF in two 25-year epochs (1965-1989 and 1990-2014).

Methods

We compared the RLR of HF at age 50 years (adjusting for competing risk of death) in the 2 epochs in Framingham Study participants overall and in the following strata: sex, body mass index, blood pressure, and diabetes.

Results

Mean life expectancy increased from 75.9 to 82.1 years in women and 72.5 to 78.1 years in men. We observed 624 HF events over 111,351 person-observations in epoch 1, and

SUBMITTER: Vasan RS 

PROVIDER: S-EPMC8820638 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature