Development of hybrid monoliths incorporating metal-organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples.

ABSTRACT: A novel coating based on hybrid monolith with metal-organic framework (MOF) onto conventional Teflon-coated magnetic stir bars was developed. For this purpose, the external surface of the Teflon stir bar was firstly vinylized in order to immobilize a glycidyl methacrylate (GMA)-based polymer onto the magnet. Then, an amino-modified MOF of type MIL-101 (NH₂-MIL-101(Al)) was covalently attached to the GMA-based monolith. After the synthesis process, several parameters affecting extraction of target estrogens by stir bar sorptive extraction (SBSE) including pH, ionic strength, extraction time, stirring rate, desorption solvent, and desorption time were also investigated. The resulting hybrid monolith was evaluated as SBSE sorbent for extraction of three estrogens (estrone, 17β-estr

SUBMITTER: Zatrochova S 

PROVIDER: S-EPMC8821068 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature