Glymphatic Dysfunction in Patients With End-Stage Renal Disease.

ABSTRACT:

Background

We aimed to compare glymphatic dysfunction between patients with end-stage renal disease (ESRD) and healthy controls and analyze the correlation between the glymphatic function and clinical characteristics using the diffusion tensor image analysis along with the perivascular space (DTI-ALPS) index.

Methods

We prospectively enrolled neurologically asymptomatic 49 patients with ESRD undergoing dialysis and 38 healthy controls. Diffusion tensor image was conducted using the same 3T scanner, and the DTI-ALPS index was calculated. We compared the DTI-ALPS index between the patients with ESRD and healthy controls. In addition, we conducted a correlation analysis between the clinical characteristics and DTI-ALPS index in patients with ESRD.

Results

There were sign

SUBMITTER: Heo CM 

PROVIDER: S-EPMC8821099 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature