Performance of free-flow field-step electrophoresis as cleanup step for the non-target analysis of environmental water samples.

ABSTRACT: For the analysis of low concentrations of micropollutants in environmental water samples, efficient sample enrichment and cleanup are necessary to reduce matrix effects and to reach low detection limits. For analytes of low and medium polarity, solid-phase extraction is used, but robust methods for the preconcentration of highly polar or ionizable analytes are scarce. In this work, field-step electrophoresis (FSE) was developed as an environmental sample cleanup technique for ionizable micropollutants and ionic transformation products. The FSE electrolyte system preconcentrated 15 acidic model analytes (pK_a from -2.2 to 9.1) present in aqueous samples in two fractions by factors of 5-10. Simultaneously, highly mobile matrix compounds were removed including inorganic ions such as

SUBMITTER: Rosch T 

PROVIDER: S-EPMC8821473 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature