Decision-making and experiences of preimplantation genetic diagnosis in inherited heart diseases: a qualitative study.

ABSTRACT: Preimplantation genetic diagnosis (PGD) ensures a disease-causing variant is not passed to the next generation, including for inherited heart diseases. PGD is known to cause significant emotional burden, but little is known about how parents experience PGD to select against inherited heart disease. We aim to understand how people with inherited heart disease, and their partners, experience and make decisions about PGD. Participants were recruited from a specialised inherited heart disease clinic. Qualitative semi-structured interviews were conducted with adult participants who had considered PGD. A semi-structured interview schedule explored overall experiences and reasons for undergoing PGD. Broad topics included experience of disease, reproductive history, psychosocial and financial cons

SUBMITTER: Yeates L 

PROVIDER: S-EPMC8821668 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature