Dataset Information

COVID-19-Induced Anosmia and Ageusia Are Associated With Younger Age and Lower Blood Eosinophil Counts.

ABSTRACT:

Background

Anosmia and ageusia are symptoms commonly associated with COVID-19, but the relationship with disease severity, onset and recovery are unclear.

Objective

To examine factors associated with anosmia and ageusia and the recovery from these symptoms in an ethnically diverse cohort.

Methods

Individuals tested for SARS-CoV-2 between March and April 2020 were eligible for the study. Randomly selected participants answered a telephone questionnaire on COVID-19 symptoms with a focus on anosmia and ageusia. Additionally, relevant past medical history and data on the COVID-19 clinical course were obtained from electronic medical records. 486 patients were in the COVID-19 group and 103 were COVID-19-negative.

Results

Patients who were younger were more likely to report anosmia and/or ageusia (odds ratio (OR) for anosmia per 1-year increase in age: 0·98, 95%CI:0-97-0·99, p = 0·003; for ageusia: 0·98, 95%CI:0·97-0·99, p = 0·005) as were patients with lower eosinophil counts (OR for anosmia per 0.1-K/μL increase in eosinophils: 0·02, 95%CI:0·001-0·46, p = 0·01, for ageusia 0·10, 95%CI:0·01-0·97, p = 0·047). Male gender was independently associated with a lower probability of ageusia (OR:0·56, 95%CI:0·38-0·82, p = 0·003) and earlier sense of taste recovery (HR:1·44, 95%CI:1·05-1·98, p = 0·02). Latinos showed earlier sense of taste recovery than white patients (HR:1·82, 95%CI:1·05-3·18, p = 0·03).

Conclusion

Anosmia and ageusia were more common among younger patients and those with lower blood eosinophil counts. Ageusia was less commonly reported among men, and time to taste recovery was earlier among both men and Latinos.

SUBMITTER: Sehanobish E

PROVIDER: S-EPMC8822197 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

COVID-19-Induced Anosmia and Ageusia Are Associated With Younger Age and Lower Blood Eosinophil Counts.

Sehanobish Esha E Barbi Mali M Fong Valerie V Kravitz Meryl M Sanchez Tejera Denise D Asad Mohammad M Matsumura Cynthia C Ferastraoaru Denisa D O'Neill Meaghan M Karagic Merhunisa M Akbar Nadeem N Bottalico Danielle M DM Patel Viraj V Peshansky Alexandre A Rangareddy Mahendra M Hudes Golda G Kim Mimi M Eisenberg Ruth R Nath Avindra A Smith Bryan R BR Ow Thomas J TJ Jerschow Elina E

American journal of rhinology & allergy 20210404 6

<h4>Background</h4>Anosmia and ageusia are symptoms commonly associated with COVID-19, but the relationship with disease severity, onset and recovery are unclear.<h4>Objective</h4>To examine factors associated with anosmia and ageusia and the recovery from these symptoms in an ethnically diverse cohort.<h4>Methods</h4>Individuals tested for SARS-CoV-2 between March and April 2020 were eligible for the study. Randomly selected participants answered a telephone questionnaire on COVID-19 symptoms w ...[more]

PMID: 33813917

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Dataset Information

COVID-19-Induced Anosmia and Ageusia Are Associated With Younger Age and Lower Blood Eosinophil Counts.

Background

Objective

Methods

Results

Conclusion

Publications

COVID-19-Induced Anosmia and Ageusia Are Associated With Younger Age and Lower Blood Eosinophil Counts.

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