Effect of sedation with inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review protocol.

ABSTRACT:

Introduction

The COVID-19 pandemic has renewed interest in the use of inhaled anaesthetics for sedation of ventilated critically ill patients. Preliminary data show that inhaled anaesthetics reduce lung inflammation, time to extubation and intensive care unit length of stay compared with intravenous sedatives. However, the impact of inhaled anaesthetics on cognitive and psychiatric outcomes is not well described in this setting. Randomised controlled trials are underway to establish if inhaled anaesthetics affect these and other patient and health system outcomes. Our aim is to summarise the known effects of inhaled sedatives on cognitive and psychiatric outcomes.

Methods and analysis

In this systematic review, we will use MEDLINE, EMBASE, and PsycINFO to identify studies fr

SUBMITTER: Cuninghame S 

PROVIDER: S-EPMC8822506 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature