The Age-Dependent Association Between Vascular Risk Factors and Depressed Mood.

ABSTRACT:

Objectives

Cumulative burden of vascular risk factors (VRFs) has been linked to an increased risk of depressed mood. However, the role of age in this association is still unclear. Here, we investigated whether VRF burden is associated with levels and changes in depressed mood and whether these associations become stronger or weaker from mid- to later life.

Method

We used longitudinal data from 5,689 participants (52-89 years) of the English Longitudinal Study of Ageing. A composite score incorporated the presence of 5 VRFs: hypertension, diabetes, smoking, obesity, and hypercholesterolemia. Second-order latent growth models were used to test whether levels and changes of depressed mood differed as a function of baseline VRF burden, and whether these associations were moderat

SUBMITTER: Blochl M 

PROVIDER: S-EPMC8824621 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature