Experimental (Re)structuring: The Clinical Trial as Turning Point Among Medical Research Participants.

ABSTRACT: Amid the growth of addiction medicine randomized controlled trials (RCTs), scholars have begun examining participants' study experiences, highlighting facilitators and barriers to enrollment. However, this work can overlook the interplay between trial participation and social-structural dimensions among people with substance use disorders linked to the social nature of use, socioeconomic marginalization, and time demands of substance procurement and use. To effectively conduct RCTs with this unique population, it is necessary to examine the broader social context of study participation. We conducted nested qualitative interviews with 22 participants involved in an RCT testing a treatment for alcohol and opioid use disorders in HIV clinics. Thematic analyses revealed social-structural circu

SUBMITTER: Jaffe K 

PROVIDER: S-EPMC8825438 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature