Characterization of cognitive function in survivors of diffuse gliomas using resting-state functional MRI (rs-fMRI).

ABSTRACT: As treatments for diffuse gliomas have advanced, survival for patients with gliomas has also increased. However, there remains limited knowledge on the relationships between brain connectivity and the lasting changes to cognitive function that glioma survivors often experience long after completing treatment. This resting-state functional magnetic resonance imaging (rs-fMRI) study explored functional connectivity (FC) alterations associated with cognitive function in survivors of gliomas. In this pilot study, 22 patients (mean age 43.8 ± 11.9) with diffuse gliomas who completed treatment within the past 10 years were evaluated using rs-fMRI and neuropsychological measures. Novel rs-fMRI analysis methods were used to account for missing brain in the resection cavity. FC relationships were a

SUBMITTER: Wang C 

PROVIDER: S-EPMC8825610 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature