Dataset Information

Racialized Economic Segregation and Breast Cancer Mortality among Women in Maryland.

ABSTRACT:

Background

Our objective was to determine the association between racialized economic segregation and the hazard of breast cancer mortality in Maryland.

Methods

Among 35,066 women (24,540 White; 10,526 Black) diagnosed with incident invasive breast cancer in Maryland during 2007 to 2017, exposure to racialized economic segregation was measured at the census tract level using Index of Concentration at the Extremes metrics. HRs and 95% confidence intervals (CI) were estimated using Cox proportional hazards regression for the association between racialized economic segregation and the hazard of breast cancer mortality, accounting for clustering at the census tract level. Models were adjusted for age and stratified by race, median age (<60 years, ≥60 years), and clinical characteristics.

Results

Overall, the hazard of breast cancer mortality was 1.84 times as high (95% CI, 1.64-2.06) for the least privileged quintile of racialized economic segregation compared with the most privileged quintile. This association differed significantly (P _interaction< 0.05) by race and age, with 1.20 (95% CI, 0.90-1.60) times the hazard of breast cancer mortality for Black women versus 1.66 (95% CI, 1.41-1.95) times the hazard for White women, and with greater hazards for younger women (HR, 2.17; 95% CI, 1.83-2.57) than older women (HR, 1.62; 95% CI, 1.40-1.88).

Conclusions

Our results suggest that breast cancer survival disparities exist in Maryland among women residing in the least privileged census tracts with lower income households and higher proportions of Black residents.

Impact

Our findings provide new insights into the breast cancer mortality disparities observed among women in Maryland.

SUBMITTER: Connor AE

PROVIDER: S-EPMC8825681 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Racialized Economic Segregation and Breast Cancer Mortality among Women in Maryland.

Connor Avonne E AE Kaur Maneet M Dibble Kate E KE Visvanathan Kala K Dean Lorraine T LT Hayes Jennifer H JH

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20211203 2

<h4>Background</h4>Our objective was to determine the association between racialized economic segregation and the hazard of breast cancer mortality in Maryland.<h4>Methods</h4>Among 35,066 women (24,540 White; 10,526 Black) diagnosed with incident invasive breast cancer in Maryland during 2007 to 2017, exposure to racialized economic segregation was measured at the census tract level using Index of Concentration at the Extremes metrics. HRs and 95% confidence intervals (CI) were estimated using ...[more]

PMID: 34862211

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Dataset Information

Racialized Economic Segregation and Breast Cancer Mortality among Women in Maryland.

Background

Methods

Results

Conclusions

Impact

Publications

Racialized Economic Segregation and Breast Cancer Mortality among Women in Maryland.

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