Evolution of an increased performance under acute challenge does not exacerbate vulnerability to chronic stress.

ABSTRACT: An adequate stress response plays a vital role in coping with challenges. However, if selection for improved coping with an acute challenge affects the entire stress response system, susceptibility to adverse effects of chronic stressors can be deepened. Here, we used bank voles from lines selected for high swim-induced aerobic metabolism (A) and unselected control (C), and asked if the selection affected sensitivity to chronic mild stress (CMS). The voles were first habituated to daily weighing and feces collection for three weeks, and then for two weeks were exposed to CMS or remained undisturbed. The habituation itself resulted in an increased swim-induced oxygen consumption in both line types, and a decreased body mass. The CMS treatment caused reduction of food consumption in the seco

SUBMITTER: Lipowska MM 

PROVIDER: S-EPMC8825808 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature