Application of ultrasound combined with noninvasive prenatal testing in prenatal testing.

ABSTRACT:

Background

Both noninvasive prenatal testing (NIPT) and prenatal ultrasound are widely used in clinical settings due to their safety, noninvasiveness, and accuracy, showing high detection rates for fetal chromosomal aneuploidies and structural abnormalities. However, whether the combined application of these two techniques has higher clinical applicability remains to be demonstrated.

Methods

The clinical and laboratory data of 3,050 pregnant women who underwent NIPT were collected. The clinical feasibility and health economics of NIPT were investigated by analyzing the accuracy, postnatal follow-up results, and population applicability of NIPT. In addition, an analysis ultrasonography, NIPT, and karyotyping results were performed to evaluate the combined application of ultra

SUBMITTER: Liu C 

PROVIDER: S-EPMC8825935 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature