Clinical application value of serum neutrophil gelatinase-associated lipocalin in neonatal sepsis.

ABSTRACT:

Background

To explore the value of serum neutrophil gelatinase-associated lipocalin (sNGAL) in the diagnosis and follow up of neonatal late-onset sepsis.

Methods

A total of 69 infants were enrolled in this prospective study, including 49 infants of late-onset neonatal sepsis in the observation group, and 20 infants without infection serving as the control group. The sNGAL, C-reactive protein (CRP), and procalcitonin (PCT) concentrations were determined in both groups and compared at different time points. A receiver operating characteristic (ROC) curve was drawn to evaluate the values of the 3 parameters in the forecast of neonatal late-onset sepsis.

Results

The levels of sNGAL, CRP, and PCT were all increased obviously (P<0.05) in the observation group on the first a

SUBMITTER: Cai Q 

PROVIDER: S-EPMC8825938 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature