Methimazole plus levothyroxine for treating hyperthyroidism in children: a systematic review and meta-analysis.

ABSTRACT:

Background

Hyperthyroidism is a disease of excessive synthesis and secretion of thyroid hormones, and there is a lack of studies that have systematically evaluated the efficacy of the combination in treating hyperthyroidism. This study aimed to systematically evaluate the effectiveness and safety of methimazole combined with levothyroxine for treating hyperthyroidism in children.

Methods

We searched PubMed, CNKI, Wanfang Database, EMBASE, Web of Science, and other online electronic databases to find correlation studies of methimazole combined with levothyroxine in treating hyperthyroidism in children from 2010 to 2021. Meta-analysis was performed using Stata 16 software.

Results

Finally, 15 relevant articles were included comprising 1,718 pediatric patients. Meta-anal

SUBMITTER: Wu X 

PROVIDER: S-EPMC8825942 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature