The Incubascope: a simple, compact and large field of view microscope for long-term imaging inside an incubator.

ABSTRACT: Optical imaging has rapidly evolved in the last decades. Sophisticated microscopes allowing optical sectioning for three-dimensional imaging or sub-diffraction resolution are available. Due to price and maintenance issues, these microscopes are often shared between users in facilities. Consequently, long-term access is often prohibited and does not allow to monitor slowly evolving biological systems or to validate new models like organoids. Preliminary coarse long-term data that do not require acquisition of terabytes of high-resolution images are important as a first step. By contrast with expensive all-in-one commercialized stations, standard microscopes equipped with incubator stages offer a more cost-effective solution despite imperfect long-run atmosphere and temperature control. Here

SUBMITTER: Badon A 

PROVIDER: S-EPMC8826139 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature