Characteristics, Outcomes, and Severity Risk Factors Associated With SARS-CoV-2 Infection Among Children in the US National COVID Cohort Collaborative.

ABSTRACT:

Importance

Understanding of SARS-CoV-2 infection in US children has been limited by the lack of large, multicenter studies with granular data.

Objective

To examine the characteristics, changes over time, outcomes, and severity risk factors of children with SARS-CoV-2 within the National COVID Cohort Collaborative (N3C).

Design, setting, and participants

A prospective cohort study of encounters with end dates before September 24, 2021, was conducted at 56 N3C facilities throughout the US. Participants included children younger than 19 years at initial SARS-CoV-2 testing.

Main outcomes and measures

Case incidence and severity over time, demographic and comorbidity severity risk factors, vital sign and laboratory trajectories, clinical outcomes, and acute COVID-19

SUBMITTER: Martin B 

PROVIDER: S-EPMC8826172 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature