Respiratory Syncytial Virus Disease Severity in Young Children.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is the leading cause of acute respiratory infections (ARIs) in hospitalized children. Although prematurity and underlying medical conditions are known risk factors, most of these children are healthy, and factors including RSV load and subgroups may contribute to severity. Therefore, we aimed to evaluate the role of RSV in ARI severity and determine factors associated with increased RSV-ARI severity in young children.

Methods

Children aged <5 years with fever and/or ARI symptoms were recruited from the emergency department (ED) or inpatient settings at Vanderbilt Children's Hospital. Nasal and/or throat swabs were tested using quantitative reverse-transcription polymerase chain reaction for common respiratory viruses, including RS

SUBMITTER: Haddadin Z 

PROVIDER: S-EPMC8826377 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature