Epidemiological and Microbiome Characterization of Black Tooth Stain in Preschool Children.

ABSTRACT:

Objective

To assess the epidemiologic attributes and microbial variations associated with extrinsic black tooth stain (BTS) among Chinese preschool children.

Methods

This cross-sectional study included 250 preschool children (3-4 years) from three kindergartens in Shanghai, China. Following clinical examination, and using a case-control design, saliva and dental plaque specimens were collected from caries-free participants with (n = 21, BTS group) and without (n = 48, control group) BTS. The chi-square test and logistic regression model were used to evaluate factors associated with BTS. 16S rRNA sequencing were used to characterize the associated microbial communities.

Results

BTS was detected in 12.4% of participants, with a mean of 13.7 black-stained t

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8826690 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature