Association of circulating cardiac biomarkers with electrocardiographic abnormalities in chronic kidney disease.

ABSTRACT:

Background

Among patients with chronic kidney disease (CKD), the circulating cardiac biomarkers soluble ST2 (SST2), galectin-3, growth differentiation factor-15 (GDF-15), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity troponin-T (hsTnT) possibly reflect pathophysiologic processes and are associated with clinical cardiovascular disease. Whether these biomarkers are associated with electrocardiographic findings is not known. The aim of this study was to test the association between serum cardiac biomarkers and the presence of electrocardiographic changes potentially indicative of subclinical myocardial disease in patients with CKD.

Methods

We performed a cross-sectional analysis using 3048 participants from the Chronic Renal Insufficiency Cohort (CR

SUBMITTER: Kula AJ 

PROVIDER: S-EPMC8826765 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature