Patient-related risk factors for late rectal bleeding after hypofractionated radiotherapy for localized prostate cancer: a single-center retrospective study.

ABSTRACT:

Background

Several studies have reported patient-related risk factors for late rectal bleeding following conventionally fractionated radiotherapy for prostate cancer. We investigated patient-related risk factors for late rectal bleeding after hypofractionated radiotherapy.

Methods

A total of 231 patients with local or locally advanced prostate cancer treated with hypofractionated radiotherapy (70 or 67.2 Gy in 28 fractions) were evaluated retrospectively. All patients received intensity-modulated radiotherapy with daily image guidance. The relationships between late rectal bleeding and risk factors like diabetes, hypertension, cirrhosis, and anticoagulant use were analyzed.

Results

During a median follow-up of 23 months, the crude rates of grade ≥ 1, grade ≥ 2, and gr

SUBMITTER: Kim TG 

PROVIDER: S-EPMC8827292 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature