The Latent Structure of Negative Symptoms in the General Population in Adolescence and Emerging Adulthood.

ABSTRACT: Negative symptoms predict adverse outcomes within psychotic disorders, in individuals at high-risk for psychosis, and in young people in the community. There is considerable interest in the dimensional structure of negative symptoms in clinical samples, and accumulating evidence suggests a 5-factor structure. Little is known about the underlying structure of negative symptoms in young people despite the importance of this developmental stage for mental health. We used confirmatory factor analysis to test the structure of parent-reported negative symptoms at mean ages 16.32 (SD 0.68, N = 4974), 17.06 (SD 0.88, N = 1469) and 22.30 (SD 0.93, N = 5179) in a community sample. Given previously reported associations between total negative symptoms and genome-wide polygenic sc

SUBMITTER: Havers L 

PROVIDER: S-EPMC8827402 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature