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Partial oral antibiotic treatment of endocarditis in patients who inject drugs: a case series.


ABSTRACT:

Background

Recent literature has demonstrated that partial oral antibiotic treatment of infectious endocarditis is non-inferior to IV therapy in select patients. Despite the rising incidence of injection drug use-related endocarditis, partial oral therapy has not been well studied in persons who inject drugs.

Objectives

To evaluate the rate of relapsed infection and 90 day mortality in patients with infectious endocarditis treated with partial oral antibiotic therapy.

Methods

Consecutive patients with infectious endocarditis treated with partial oral antibiotic therapy were identified by study investigators and reviewed by independent clinicians. The decision to use partial oral antibiotic therapy was made by the institution's multidisciplinary endocarditis team.

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SUBMITTER: Miller K 

PROVIDER: S-EPMC8827559 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature