Economic evaluation of varicella vaccination strategies in Jiangsu province, China: a decision-tree Markov model.

ABSTRACT: This study evaluated different varicella vaccination strategies in Jiangsu province, China. A decision-tree Markov model was used to evaluate the cost effectiveness of various varicella vaccination strategies for children, including direct and selective vaccination (serotesting pre-vaccination). A cohort of one-year-old children was followed through 60 one-year Markov cycles. The parameter estimation was based on field work, the literature, and statistical yearbooks. We calculated the incremental cost-utility ratio (ICUR) using the saved quality-adjusted life year (QALY). One-way and probability sensitivity analyses were performed to assess uncertainty. Among 100,000 cohort members, one-dose and two-dose direct vaccination averted 8061 and 10,701 varicella cases, respectively, compared wit

SUBMITTER: Wang Q 

PROVIDER: S-EPMC8828140 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature