Photoacoustic imaging of fresh human surgically and endoscopically resected gastrointestinal specimens.

ABSTRACT:

Objective

Photoacoustic (PA) imaging is a novel noninvasive technique that offers high-contrast tomographic imaging with ultrasound-like resolution at depths of centimeters, enabling visualization of deep small vessels. The aim of this pilot study was to survey the characteristics of deep vessel networks in the mucosa of neoplastic gastrointestinal (GI) lesions using PA imaging.

Methods

Specimens of patients who had undergone surgical and endoscopic resection for GI lesions were included in this study. The PA/ultrasound imaging system for clinical research is characterized by a technology that can superimpose a PA image over an ultrasound image. Three-dimensional PA images were acquired for the resected specimen before fixation. The stomach and colon of live pigs were incise

SUBMITTER: Ikematsu H 

PROVIDER: S-EPMC8828192 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature