Establishing a prognostic model for metachronous second squamous cell lung cancer in patients with resected squamous cell lung cancer.

ABSTRACT:

Background

For metachronous second pulmonary squamous cell carcinoma (msPSC) in patients with resected PSC, the method to distinguish tumour clonality has not yet been well established, which makes it difficult to determine accurate staging and predict prognosis.

Methods

Patients who underwent surgery for first PSC and encountered msPSC were recruited from the Surveillance, Epidemiology, and End Results (SEER) database. We extracted overall survival 1 (OS1) for the first PSC, overall survival 2 (OS2) for msPSC, and interval survival for the time interval between the first and second PSC. The nomogram was calibrated for OS2, and recursive partitioning analysis (RPA) was performed for risk stratification.

Results

A total of 617 patients were identified. Several independ

SUBMITTER: Fu SS 

PROVIDER: S-EPMC8828508 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature