Study on The Anti-Inflammatory Effects of Callicarpa nudiflora Based on The Spectrum-Effect Relationship.

ABSTRACT: Callicarpa nudiflora (C. nudiflora) is widely used to treat inflammation-related diseases in China. C. nudiflora mainly contains phenylethanol glycosides, flavonoids, triterpenes, diterpenes, iridoid glycosides, volatile oils, and other small molecules. Therefore, it is necessary to screen out anti-inflammatory active substances from C. nudiflora. In this paper, high-performance liquid chromatography was used to establish the fingerprint of C. nudiflora extracts. The anti-inflammation of C. nudiflora extracts were evaluated by the experiment of toes swelling in inflammatory rats. Then, the spectrum-effect relationship between the fingerprints and anti-inflammatory activities was researched by Pearson analysis and orthogonal partial least squares an

SUBMITTER: Li Y 

PROVIDER: S-EPMC8829221 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature