Early clinical and microbiological predictors of outcome in hospitalized patients with cryptococcal meningitis.

ABSTRACT:

Background

Cryptococcal meningitis causes high mortality in immunocompromised and immunocompetent patients. The objective of this study was to identify early predictors of clinical outcome, available at the first days of hospitalization, in patients with cryptococcal meningitis in a tertiary center in Brazil.

Methods

Ninety-six cases of cryptococcal meningitis with clinical, epidemiological and laboratory data, and identification and antifungal susceptibility of the strains were analyzed. Quantitative CSF yeast counts were performed by direct microscopic exam with a Fuchs-Rosenthal cell counting chamber using an institutional protocol. Univariable and multiple analyses using logistic regression were performed to identify predictors, available at the beginning of hospitalizat

SUBMITTER: de Oliveira L 

PROVIDER: S-EPMC8830130 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature