Composite outcomes in observational studies of ulcerative colitis: A systematic review and meta-analysis.

ABSTRACT:

Background

Ulcerative colitis (UC) has been the focus of numerous observational studies over the years and a common strategy employed in their design is the use of composite and aggregate outcomes.

Objective

This systematic review and meta-analysis aims to identify composite and aggregate outcomes of observational studies in UC and to evaluate how the number and type of variables included and the length of follow-up affect the frequency of patients that achieve these outcomes.

Methods

A systematic literature search was carried out using MEDLINE [via PubMed], Scopus, and Web of Science online databases. Observational studies that included UC patients and reported composite or aggregate outcomes were identified. A set of variables considered to be representative of prog

SUBMITTER: Magro F 

PROVIDER: S-EPMC8830283 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature