Effects of substituting soybean meal with corn on immune function and gene expression of gut TLR4 pathway of growing goats.

ABSTRACT:

Background

Protein malnutrition remains a severe problem in ruminant production and can increase susceptibility to infection, especially during the growth stage. This study aimed to explore substituting soybean meal with corn on activation of the TLR pathway and potential impact on immune response bias towards Type 1 or Type 2 using growing female goats as experimental animals.

Methods

Twenty-four Xiangdong black goats (initial BW = 19.83 ± 0.53 kg, about 8 ± 0.3 months old) were selected and randomly divided into the corn-soybean meal basal diet group (CON, 10.77% protein) and replacing soybean meal with 100% of corn group (CRS, 5.52% protein). EDTA whole blood and serum samples were collected prior to slaughter for determinations of blood cell counts, anti-inflammatory cyt

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC8830315 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature