Importance of sex and gender in ischaemic stroke and carotid atherosclerotic disease.

ABSTRACT: Stroke is a leading cause of death and disability worldwide. Women are disproportionately affected by stroke, exhibiting higher mortality and disability rates post-stroke than men. Clinical stroke research has historically included mostly men and studies were not properly designed to perform sex- and gender-based analyses, leading to under-appreciation of differences between men and women in stroke presentation, outcomes, and response to treatment. Reasons for these differences are likely multifactorial; some are due to gender-related factors (i.e. decreased social support, lack of stroke awareness), yet others result from biological differences between sexes. Unlike men, women often present with 'atypical' stroke symptoms. Lack of awareness of 'atypical' presentation has led to delays in

SUBMITTER: Gasbarrino K 

PROVIDER: S-EPMC8830529 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature