Wave-shaped microfluidic chip assisted point-of-care testing for accurate and rapid diagnosis of infections.

ABSTRACT:

Background

Early diagnosis and classification of infections increase the cure rate while decreasing complications, which is significant for severe infections, especially for war surgery. However, traditional methods rely on laborious operations and bulky devices. On the other hand, point-of-care (POC) methods suffer from limited robustness and accuracy. Therefore, it is of urgent demand to develop POC devices for rapid and accurate diagnosis of infections to fulfill on-site militarized requirements.

Methods

We developed a wave-shaped microfluidic chip (WMC) assisted multiplexed detection platform (WMC-MDP). WMC-MDP reduces detection time and improves repeatability through premixing of the samples and reaction of the reagents. We further combined the detection platform with t

SUBMITTER: Yin BF 

PROVIDER: S-EPMC8831027 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature