Preventive effect of biodegradable stents on biliary stricture and fibrosis after biliary anastomosis in a porcine model.

ABSTRACT:

Purpose

The current drain tubes for preventing surgically biliary anastomotic stricture are not naturally and easily removed. If a drain tube using biodegradable material is easily available and the degradation time of the tube is well controlled, surgical anastomotic stricture and fibrosis could be prevented. The aim of this animal study was to evaluate the preventive effect of novel biodegradable stents (BS) on biliary stricture and fibrosis after duct-to-duct (DD) biliary anastomosis.

Methods

Ten mini-pigs were allocated to the control group (n = 5) and or the stent group (n = 5). The common bile duct was exposed through surgical laparotomy and then resected transversely. In the stent group, a 4-mm or 6-mm polydioxanone/magnesium sheath-core BS was inserted according to t

SUBMITTER: Kwon CI 

PROVIDER: S-EPMC8831087 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature