Acute Lesion Imaging in Predicting Chronic Tissue Injury in the Ventricles.

ABSTRACT:

Background

Chronic lesion formation after cardiac tissue ablation is an important indicator for procedural outcome. Moreover, there is a lack of knowledge regarding the features that predict chronic lesion formation.

Objective

The aim of this study is to determine whether acute lesion visualization using late gadolinium enhanced magnetic resonance imaging (LGE-MRI) can reliably predict chronic lesion size.

Methods

Focal lesions were created in left and right ventricles of canine models using either radiofrequency (RF) ablation or cryofocal ablation. Multiple ablation parameters were used. The first LGE-MRI was acquired within 1-5 h post-ablation and the second LGE-MRI was obtained 47-82 days later. Corview software was used to perform lesion segmentations and size cal

SUBMITTER: El Hajjar AH 

PROVIDER: S-EPMC8831749 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature