Poor Sleep Quality Associated With Enlarged Perivascular Spaces in Patients With Lacunar Stroke.

ABSTRACT:

Background and objective

Enlarged perivascular spaces (EPVSs) are considered as an MRI marker of cerebral small vessel diseases and were reported to be associated with brain waste clearance dysfunction. A previous study found that interstitial fluid clearance in the mouse brain occurred mainly during sleep. However, the relationship between sleep quality and EPVS in humans has not been well-understood. Thus, we aimed to investigate the relationship between sleep and EPVS in humans.

Methods

This retrospective study was conducted in patients with lacunar stroke in the Neurology Department of Beijing Chaoyang Hospital. Patients with EPVS >10 on one side of the basal ganglia (BG) and white matter slice containing the maximum amount were defined as the BG-EPVS group and the white

SUBMITTER: Yang S 

PROVIDER: S-EPMC8831757 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature