Association of Infantile Hemangiomas and Retinopathy of Prematurity: Analysis of the Multicenter KID.

ABSTRACT:

Introduction

Retinopathy of prematurity (ROP) and infantile hemangiomas (IHs) both have similar proposed pathophysiological mechanisms. IH is more common in preterm than term infants. Hypoxia-induced mediators like vascular endothelial growth factor have been found elevated in children with hemangiomas. The aim of our study was to determine if there is an association between ROP and IH in preterm infants and to investigate racial/ethnic and gender differences of ROP and IHs in this cohort.

Methods

We accessed the national multicenter Kids' Inpatient Database (KID) Healthcare Cost and Utilization Project (HCUP) including admissions at age ≤28 days. Eligible infants were identified by using ICD-9 codes of ROP and IH in infants with gestational age (GA) ≤32 weeks and/or birth w

SUBMITTER: Dankhara N 

PROVIDER: S-EPMC8832195 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature