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Visible-Light Driven Selective C-N Bond Scission in anti-Bimane-Like Derivatives.

ABSTRACT: In the present study, we report the photochemical transformation of pyrazolo[1,2-a]pyrazolone substrates that reach an excited state upon irradiation with visible light to initiate the homolytic C-N bond cleavage process that yields the corresponding N1-substituted pyrazoles. Moreover, chemoselective heterolytic C-N bond cleavage is possible in the pyrazolo[1,2-a]pyrazole core in the presence of bromomalonate.

SUBMITTER: Petek N

PROVIDER: S-EPMC8832495 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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Visible-Light Driven Selective C-N Bond Scission in anti-Bimane-Like Derivatives.

Petek Nejc N Brodnik Helena H Grošelj Uroš U Svete Jurij J Požgan Franc F Štefane Bogdan B

Organic letters 20210602 14

In the present study, we report the photochemical transformation of pyrazolo[1,2-a]pyrazolone substrates that reach an excited state upon irradiation with visible light to initiate the homolytic C-N bond cleavage process that yields the corresponding N1-substituted pyrazoles. Moreover, chemoselective heterolytic C-N bond cleavage is possible in the pyrazolo[1,2-a]pyrazole core in the presence of bromomalonate. ...[more]

PMID: 34077227

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