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Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021.

ABSTRACT: The SARS-CoV-2 Omicron variant has a growth advantage over the Delta variant because of higher transmissibility, immune evasion or shorter serial interval. Using S gene target failure (SGTF) as indication for Omicron BA.1, we identified 908 SGTF and 1,621 non-SGTF serial intervals in the same period. Within households, the mean serial interval for SGTF cases was 0.2-0.6 days shorter than for non-SGTF cases. This suggests that the growth advantage of Omicron is partly due to a shorter serial interval.

SUBMITTER: Backer JA 

PROVIDER: S-EPMC8832521 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021.

Backer Jantien A JA   Eggink Dirk D   Andeweg Stijn P SP   Veldhuijzen Irene K IK   van Maarseveen Noortje N   Vermaas Klaas K   Vlaemynck Boris B   Schepers Raf R   van den Hof Susan S   Reusken Chantal Bem CB   Wallinga Jacco J  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20220201 6

The SARS-CoV-2 Omicron variant has a growth advantage over the Delta variant because of higher transmissibility, immune evasion or shorter serial interval. Using S gene target failure (SGTF) as indication for Omicron BA.1, we identified 908 SGTF and 1,621 non-SGTF serial intervals in the same period. Within households, the mean serial interval for SGTF cases was 0.2-0.6 days shorter than for non-SGTF cases. This suggests that the growth advantage of Omicron is partly due to a shorter serial inte  ...[more]

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